Human satellite 3 (HS3) binding protein from the nuclear matrix: isolation and binding properties

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DNA-binding properties of nuclear matrix proteins.

Mouse nuclear matrix proteins, examined by a filter assay, were found to bind to DNA. There was no preference for homologous mouse compared to heterologous E. coli DNA. Competition assays showed a preference for AT-rich DNA and of the 4 single-stranded homopolymers there was a preference for poly(dT). These observations are consistent with the possibility that the matrix may play a role in the ...

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ژورنال

عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

سال: 2000

ISSN: 0167-4889

DOI: 10.1016/s0167-4889(00)00042-2